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NCT00919594: IPT-MOMS
Psychotherapy for Depressed Mothers of Psychiatrically Ill
NA trial testing Interpersonal Psychotherapy for Mothers (IPT-MOMS) in Depression in 348 participants. Completed in 1 February 2014.
1 February 2014
Quick facts
| Lead sponsor | University of Pittsburgh |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 348 |
| Start date | 1 August 2009 |
| Primary completion | 1 February 2014 |
| Estimated completion | 1 February 2014 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Interpersonal Psychotherapy for Mothers (IPT-MOMS)
- Brief Supportive Psychotherapy
Conditions studied
- Depression — all drugs for Depression →
Sponsor
University of Pittsburgh
Who can join
Adults 7 to 65, any sex, with Depression. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
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We will compare the effects of two interventions IPT-MOMS and BSP on children outcomes: depressive symptoms (as measured by the CDI), total difficulties (as measured by the SDQ), and psychosocial functioning (as measured by the CIS) over time
Time frame: Baseline, Months 3, 6, 9, 12 -
We will compare the two groups in depressive symptoms (as measured by the HRSD-25) and psychosocial and vocational functioning (as measured by the IIP, ISEL, and WSAS) over time.
Time frame: Baseline, Months 3, 6, 9, 12
Sponsor's own description
The current proposal is a randomized, controlled, clinical trial to evaluate the intergenerational impact of treating depressed mothers whose children suffer from psychiatric disorders.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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Brief Psychotherapy for Maternal Depression: Impact on Mothers and Children.
Swartz HA, Cyranowski JM, Cheng Y, Zuckoff A, et al · · 2016 · cited 27× · PMID 27238068 · DOI 10.1016/j.jaac.2016.04.003
Verify or expand the search:
- PubMed search for NCT00919594
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Pittsburgh trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00919594 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Pittsburgh
- Last refreshed: 14 July 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00919594.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing