Prevention Relapse of Graves' Disease by Treatment With Intrathyroid Injection of Dexamethasone

NCT00917241 Phase 4 COMPLETED

Antithyroid drugs are widely used in treatment of Graves' disease (GD), but after therapy withdrawal, relapse rate is very high. The aim this trail is to evaluate the effects of intrathyroid injection of dexamethasone combined with antithyroid drugs on patients with newly diagnosed GD.

Details

Lead sponsor	Xiao-Ming Mao
Phase	Phase 4
Status	COMPLETED
Enrolment	218
Start date	2004-06
Completion	2009-03

Conditions

• Graves' Disease

Interventions

• MMI combined with IID
• MMI

Primary outcomes

• relapse of hyperthyroidism — 4.5 year