Who is sponsoring NCT00905762?

NCT00905762 is sponsored by Bausch & Lomb Incorporated.

What drugs are being tested in NCT00905762?

Interventions: Gatifloxacin, Moxifloxacin, Besifloxacin.

What is the status of NCT00905762?

NCT00905762 is currently COMPLETED.

Last reviewed 2011-12-07 · How we verify

A Single-Center, Randomized, Masked Study Comparing the Concentration of Besifloxacin, Gatifloxacin, and Moxifloxacin in Human Conjunctiva After a Single Topical Instillation

NCT00905762 Phase 1 COMPLETED

The purpose of this study is to assess the concentration of besifloxacin compared to gatifloxacin and moxifloxacin in human conjunctival tissue, following a single drop of the drug instilled topically into the study eye. Conjunctival biopsies will be performed at specified time points, followed by the use of loteprednol etabonate/tobramycin ophthalmic suspension four times a day for 5 days.

Details

Lead sponsor	Bausch & Lomb Incorporated
Phase	Phase 1
Status	COMPLETED
Enrolment	119
Start date	2009-03
Completion	2009-04

Conditions

Healthy

Interventions

Gatifloxacin
Moxifloxacin
Besifloxacin

Primary outcomes

Concentration of besifloxacin, gatifloxacin or moxifloxacin in conjunctival tissue. — Biopsies collected at specified time points from 15 minutes to 24 hours

Countries

United States