A Randomised Comparison of Anastrozole Commenced Before and Continued During Adjuvant Radiotherapy for Breast Cancer Versus Anastrozole and Subsequent Anti-oestrogen Therapy Delayed Until After Radiotherapy. (STARS)

NCT00887380 Phase 3 UNKNOWN

The purpose of this study is to determine whether starting anastrozole prior to radiotherapy, so that it is taken during radiotherapy, decreases local recurrence of breast cancer in post-menopausal women in comparison to waiting until after radiotherapy to commence anastrozole.

Details

Lead sponsor	Trans Tasman Radiation Oncology Group
Phase	Phase 3
Status	UNKNOWN
Enrolment	2023
Start date	2009-09-16
Completion	2024-12

Conditions

• Breast Cancer

Interventions

• Pre-radiotherapy commencement of anastrozole
• Radiotherapy
• Post radiotherapy commencement of anastrozole

Primary outcomes

• To determine if commencement of anastrozole prior to radiotherapy results in improved local control compared to anastrozole commenced after radiotherapy. — 10 years post radiotherapy

Countries

Australia, New Zealand