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Phase I Study of Gemcitabine, Capecitabine, and Erlotinib Together in Advanced Pancreatic Cancers
RATIONALE: Drugs used in chemotherapy, such as gemcitabine and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I trial is studying the side effects and best dose of gemcitabine given together with capecitabine and erlotinib in treating patients with advanced pancreatic cancer.
Details
| Lead sponsor | Centre Antoine Lacassagne |
|---|---|
| Phase | Phase 1 |
| Status | COMPLETED |
| Enrolment | 30 |
| Start date | 2008-05 |
| Completion | 2009-10 |
Conditions
- Pancreatic Cancer
Interventions
- capecitabine
- erlotinib hydrochloride
- gemcitabine hydrochloride
Primary outcomes
- Clinical or laboratory toxicities as assessed by CTC — 1 year
Countries
France