Last reviewed · How we verify
LC Drug Eluting Bead for Regional Chemoembolization to Downstage Unresectable Hepatocellular Carcinoma (HCC) to Liver Transplantation
Advanced HCC represents a high unmet medical need with a poor prognosis and few therapeutic options. Patients who present with HCC beyond the currently accepted Milan criteria are not eligible to be listed for liver transplantation. The proposed study offers local regional therapy to a defined population of patients beyond Milan criteria as an attempt to downstage them to eligibility for liver transplant.
Details
| Lead sponsor | University of Pittsburgh |
|---|---|
| Phase | Phase 2 |
| Status | COMPLETED |
| Enrolment | 2 |
| Start date | 2008-11 |
| Completion | 2012-04 |
Conditions
- Hepatocellular Carcinoma
Interventions
- LC Bead loaded with doxorubicin
Primary outcomes
- The Number of Patients in the Cohort Effectively Downstaged to Transplant Eligibility With the LC BeadTM — 36 months
Advanced HCC represents a high unmet medical need with a poor prognosis and few therapeutic options. Patients who present with HCC beyond the currently accepted Milan criteria are not eligible to be listed for liver transplantation. The proposed study offers local regional therapy to both a defined population of patients beyond Milan criteria as an attempt to downstage them to eligibility for liver transplant as well as those individuals within Milan criteria as an attempt to maintain their eligibility.
Countries
United States