NCT00872950 (LEMS) is a clinical trial of 3,4-DIAMINOPYRIDINE in Lambert-Eaton Myasthenic Syndrome, sponsored by Lahey Clinic.

Who is sponsoring NCT00872950?

NCT00872950 is sponsored by Lahey Clinic.

What drugs are being tested in NCT00872950?

Interventions in NCT00872950: 3,4-DIAMINOPYRIDINE.

What condition does NCT00872950 study?

NCT00872950 studies Lambert-Eaton Myasthenic Syndrome, Congenital Myasthenic Syndrome.

Is NCT00872950 still recruiting?

NCT00872950 is currently approved for marketing. Last updated 11 April 2022.

Last reviewed 2022-04-11 · How we verify

NCT00872950: LEMS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

3,4-Diaminopyridine Use in Lambert-Eaton Myasthenic Syndrome(LEMS) and Congenital Myasthenic Syndromes (CMS)

APPROVED FOR MARKETING Last updated 11 April 2022

What this trial tests

trial testing 3,4-DIAMINOPYRIDINE in Lambert-Eaton Myasthenic Syndrome. Approved for marketing.

Quick facts

Lead sponsor	Lahey Clinic
Status	APPROVED FOR MARKETING
Study type	EXPANDED_ACCESS
Sites	1 location across United States

Drugs / interventions tested

3,4-DIAMINOPYRIDINE — full drug profile →

Conditions studied

Lambert-Eaton Myasthenic Syndrome — all drugs for Lambert-Eaton Myasthenic Syndrome →
Congenital Myasthenic Syndrome — all drugs for Congenital Myasthenic Syndrome →

Sponsor

Lahey Clinic

Who can join

18 and older, any sex, with Lambert-Eaton Myasthenic Syndrome or Congenital Myasthenic Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine the effectiveness and adverse effects of 3,4-diaminopyridine for the treatment of the Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenic Syndromes (CMS).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Treating pediatric neuromuscular disorders: The future is now.
Dowling JJ, D Gonorazky H, Cohn RD, Campbell C. · · 2018 · cited 83× · PMID 28889642 · DOI 10.1002/ajmg.a.38418
The Importance of Early Treatment of Inherited Neuromuscular Conditions.
Mackels L, Servais L. · · 2024 · cited 6× · PMID 38306060 · DOI 10.3233/jnd-230189

Verify or expand the search:

Other recruiting trials for Lambert-Eaton Myasthenic Syndrome

Currently open trials in the same condition.

NCT06441825 — Patient Observation With Environmental and Wearable Sensors in Myasthenia Gravis · recruiting

Other Lahey Clinic trials

Trials by the same sponsor.

NCT06868589 — Reducing Pain With Methadone and Ketamine in Liver Transplant · Phase 4 · active not recruiting
NCT07187063 — Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer · NA · recruiting
NCT04844970 — Anamorelin Study for Advanced Pancreatic Cancer · Phase 2 · terminated
NCT04077749 — Probiotic Bladder Instillation for Prevention of Catheter Associated UTIs in Chronically Catheterized Patients · EARLY_PHASE1 · withdrawn
NCT05993195 — Re-operation Rates of Concorde Bullet Device Versus Conduit Titanium Interbody Graft for Lumbar Fusion · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00872950 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Lahey Clinic
Last refreshed: 11 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00872950.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing