NCT00869180 (SUPPORT 2) is a Phase 3 clinical trial of Diclofenac Sodium in Acute Pain, sponsored by Cerimon Pharmaceuticals.

Who is sponsoring NCT00869180?

NCT00869180 is sponsored by Cerimon Pharmaceuticals.

What drugs are being tested in NCT00869180?

Interventions in NCT00869180: Diclofenac Sodium, Matching Placebo Patch.

What condition does NCT00869180 study?

NCT00869180 studies Acute Pain, Ankle Sprain.

Is NCT00869180 still recruiting?

NCT00869180 is currently completed. Last updated 26 January 2010.

Last reviewed 2010-01-26 · How we verify

NCT00869180: SUPPORT 2

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of a Diclofenac Sodium Patch for the Topical Treatment of Acute Pain Due to Mild to Moderate Ankle Sprain

Completed Phase 3 Last updated 26 January 2010

What this trial tests

Phase 3 trial testing Diclofenac Sodium in Acute Pain in 219 participants. Completed in 1 August 2009.

Timeline

1 February 2009

Primary endpoint
1 June 2009

1 August 2009

Quick facts

Lead sponsor	Cerimon Pharmaceuticals
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	219
Start date	1 February 2009
Primary completion	1 June 2009
Estimated completion	1 August 2009
Sites	1 location across United States

Drugs / interventions tested

Diclofenac Sodium (Diclofenac Sodium) — full drug profile →
Matching Placebo Patch

Conditions studied

Acute Pain — all drugs for Acute Pain →
Ankle Sprain — all drugs for Ankle Sprain →

Sponsor

Cerimon Pharmaceuticals

Who can join

Adults 17 to 75, any sex, with Acute Pain or Ankle Sprain. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Change in average pain during daily activity at Day 3
Time frame: Day 3

Sponsor's own description

The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium topical patch in reducing acute pain due to mild to moderate ankle sprains when applied to the painful area.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Topical NSAIDs for acute musculoskeletal pain in adults.
Derry S, Moore RA, Gaskell H, McIntyre M, et al · · 2015 · cited 74× · PMID 26068955 · DOI 10.1002/14651858.cd007402.pub3

Verify or expand the search:

Other trials of Diclofenac Sodium

Trials testing the same drug.

NCT07131527 — Comparison Between Oral Gabapentin Versus Diclofenac Sodium in Post-operative Analgesia Laparoscopic Cholecystectomy · NA · recruiting
NCT06111573 — Comparative Evaluation of the Effectiveness of Diclofenac Sodium Versus Vitamin D on Myofascial Pain · Phase 4 · completed
NCT05313997 — The Incidence of Thoracic Disc Herniation in Patients Presenting With Chronic Upper Back Pain · completed
NCT05626140 — COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA · Phase 3 · completed
NCT05488925 — Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block. · Phase 4 · completed

Other recruiting trials for Acute Pain

Currently open trials in the same condition.

NCT06779604 — Dexmedetomidine and Dexamethasone Added as Adjuvant Infraclavicular Brachial Plexus Block in Upper Limb Surgery · recruiting
NCT07348419 — Quadro-Iliac vs Thoracolumbar Interfascial Plane Block for Analgesia After Single-Level Lumbar Disc Surgery · NA · recruiting
NCT07335159 — Does Patient Testimonial Improve the Pain Relief Derived From a Brief Intervention · NA · recruiting
NCT07348523 — Comparison of the Postoperative Analgesic Efficacy of Classical and Modified Erector Spinae Plane Blocks After Lumbar Sp · NA · recruiting
NCT07336264 — Characterization of Acute Pain · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00869180 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cerimon Pharmaceuticals
Last refreshed: 26 January 2010

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00869180.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing