A Randomized Comparative Clinical Trial of ZDV + 3TC + ABC (Trizivir) vs Monotherapy With Lopinavir/R (Kaletra) in Patients With Viral Suppression on Previous Treatment With ZDV + 3TC + ABC (Trizivir) for Preventing Lipoatrophy (KALIPO)

NCT00865475 Phase 4 COMPLETED

The aim of this study is to measure the prevention of lipoatrophy in patients treated with Lopinavir/R in monotherapy versus ZDV + 3TC + ABC

Details

Lead sponsor	Fundacion SEIMC-GESIDA
Phase	Phase 4
Status	COMPLETED
Enrolment	38
Start date	2008-12
Completion	2013-03

Conditions

• HIV Infection
• HIV Infections

Interventions

• AZT+3TC+ABV (Trizivir)
• Switching to LPV/r monotherapy (Kaletra)

Primary outcomes

• Limb Fat changes measured by DEXA — 48 weeks

Countries

Spain