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PeriOperative ISchemic Evaluation-2 (POISE-2) Trial: A Pilot (POISE2-pilot)
Major non-cardiac surgeries are common and major heart problems during or after such surgeries represent a large population health problem. Few treatments to prevent heart problems around the time of surgery have been tested. There is encouraging data suggesting that low-doses of Acetyl-Salicylic Acid (ASA) and Clonidine, which are two medications, given individually for a short period before and after major surgeries may prevent major heart problems.
Details
| Lead sponsor | McMaster University |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 90 |
| Start date | 2009-05 |
| Completion | 2010-01 |
Conditions
- Cardiovascular Disease
Interventions
- active clonidine
- active ASA
- Clonidine Placebo
- ASA Placebo
Primary outcomes
- Feasibility of recruiting 90 patients in 6 months — 6 months
Countries
Canada, China