Who is sponsoring NCT00859196?

NCT00859196 is sponsored by Bayer.

What condition does NCT00859196 study?

NCT00859196 studies Wound Healing, Cell Proliferation, Gene Expression.

What drugs are being tested in NCT00859196?

Interventions: Dexpanthenol (BAY81-2996), Placebo.

What is the status of NCT00859196?

NCT00859196 is currently COMPLETED.

Last reviewed 2014-12-08 · How we verify

A Randomized, Double-blind, Single Centre, Placebo-controlled Pilot Study to Assess on a Molecular Level the Influence of a 5 % Dexpanthenol Ointment in Subjects With Previously Injured Skin by Investigation of Skin Biopsies

NCT00859196 Phase 4 COMPLETED

In previous in vitro studies it could be shown, that Dexpanthenol has an influence on the gene expression of fibroblasts. The genes which are influenced by Dexpanthenol play mainly a role during cell proliferating processes.The aim of this study is to investigate the molecular effect of Dexpanthenol on human living skin, during wound healing.

Details

Lead sponsor	Bayer
Phase	Phase 4
Status	COMPLETED
Enrolment	15
Start date	2009-02
Completion	2009-03

Conditions

Wound Healing
Cell Proliferation
Gene Expression

Interventions

Dexpanthenol (BAY81-2996)
Placebo

Primary outcomes

Investigation of gene expression in dermal fibroblasts and keratinocytes on a molecular level. — Analysis of skin biopsies taken 24h, 72h and 144h after wounding

Countries

Germany