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A Study to Examine the Effects of Esomeprazole on the Pharmacokinetics of Orally Administered Lapatinib in Subjects With Metastatic ErbB2 Positive Breast Cancer

NCT00849329 PHASE1 COMPLETED

This study will characterize the effect of elevated gastric pH mediated by the proton-pump inhibitor, esomeprazole, on the relative bioavailability of lapatinib in subjects with metastatic ErbB2 positive breast cancer.

Details

Lead sponsorGlaxoSmithKline
PhasePHASE1
StatusCOMPLETED
Enrolment12
Start dateTue Mar 10 2009 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionTue Nov 24 2009 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

United States, Spain, South Korea