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A Randomised, Double Blind Trial Comparing Arimidex Alone With Nolvadex Alone With Arimidex and Nolvadex in Combination, as Adjuvant Treatment in Post-Menopausal Women With Breast Cancer
The aim of this study is to test whether Arimidex alone or in combination with Tamoxifen is beneficial in the treatment of breast cancer.
Details
| Lead sponsor | AstraZeneca |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 9358 |
| Start date | 1996-07 |
| Completion | 2010-04 |
Conditions
- Breast Cancer
Interventions
- Anastozole (Arimidex)
- Tamoxifen (Nolvadex)
- Anastozole (Arimidex) placebo
- Tamoxifen (Nolvadex) placebo
Primary outcomes
- Time to recurrence of breast cancer — Earliest of local or distant recurrence, new primary breast cancer, or death
- Safety and side effects — Earliest of local or distant recurrence, new primary breast cancer, or death