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Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne
To compare the efficacy and safety of Benzoyl peroxide used in combination with clindamycin vs. Benzoyl peroxide used in combination with clindamycin and doxycycline in the treatment of moderate acne
Details
| Lead sponsor | Stiefel, a GSK Company |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 33 |
| Start date | 2007-08 |
| Completion | 2008-08 |
Conditions
- Acne
Interventions
- Benzoyl peroxide with clindamycin
- Benzoyl peroxide with clindamycin and doxycycline
Primary outcomes
- Percent Change in Inflammatory Acne Lesions From Baseline to Week 16 — Baseline, Week 16
Percent change from baseline to week 16 in inflammatory acne lesions (pustules/papules)(chest and back) - Percent (%) Change in Non-inflammatory Acne Lesions From Baseline to Week 16. — Baseline, Week 16
Percent change in Non-inflammatory acne lesions (whiteheads and blackheads)(chest and back) from baseline to week 16. - Percent Change in Total Acne Lesion Counts From Baseline to Week 16 — Baseline, Week 16
Percent change from baseline to week 16 in total acne lesions (inflammatory + non-inflammatory) - Change in Investigator Global Assessment (IGA) — Baseline, Weeks 4, 8,12, and 16
Change in Investigator Global Assessment (IGA) Average values chest and back. IGA scale: 0 - Clear 0.5 - Clear/almost clear 1. Almost Clear 1.5- Almost Clear/Mild 2. Mild 2.5- Mild/Moderate 3. Moderate 3.5- Moderate/Severe
Countries
United States