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A Randomized, Double-Blind Comparison of Oral Aprepitant and Lower Dose Dexamethasone vs Aprepitant Alone for Preventing Postoperative Nausea and Vomiting After Elective Laparoscopic Surgeries
The combination of aprepitant and lower dose dexamethasone is superior to aprepitant alone with respect to the proportion of patients with a complete response (no vomiting and no use of rescue therapy) during 24 hours after the placement of last suture/staple.
Details
| Lead sponsor | Main Line Health |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 50 |
| Start date | 2009-02 |
Conditions
- Nausea
- Vomiting
Interventions
- Dexamethasone
- Aprepitant
- Placebo Dexamethasone
Primary outcomes
- the incidences of nausea, vomiting, need for rescue medication — 1 hour, 2 hours, 24 hours after surgery
Countries
United States