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A Clinical Trial of Renin Profiling in Selection of Initial Antihypertensive Drug
The purpose of this research study is to determine whether a simple blood test measuring a hormone called renin can better determine which first drug would be most effective in controlling blood pressure, in comparison with the more traditional approach recommended by JNC7 (Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure).
Details
| Lead sponsor | The Louis & Rachel Rudin Foundation |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 185 |
| Start date | 2005-12 |
| Completion | 2011-10 |
Conditions
- Hypertension
Interventions
- olmesartan, hydrochlorothiazide, amlodipine
- hydrochlorothiazide (HCTZ) or olmesartan
Primary outcomes
- Percent of patients with BP <140/90 mmHg and on monotherapy at the 5th visit. — 3-4 months
Countries
United States