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Prospective, Randomized, Observational Cohort Study of Antibiotic Resistance After Repeated Application of Topical Antibiotics (ARCaNE)
Repeated exposure to topical antibiotics may alter the normal bacteria on the eye and in the nose and increase rates of resistance. This study will determine whether repeated short-term exposure to topical antibiotic drops which are commonly prescribed after eye injections to reduce the chance of infection increase rates of resistant bacteria which are normally found on the eye and in the nose. We hypothesis that certain commercially available antibiotics may increase rates of bacteria resistance more so than others.
Details
| Lead sponsor | Vanderbilt University |
|---|---|
| Status | COMPLETED |
| Enrolment | 24 |
| Start date | 2009-01 |
Conditions
- Age-related Macular Degeneration
Interventions
- Conjunctival and nasopharyngeal bacteria cultures
Primary outcomes
- Establish baseline susceptibility and resistance patterns of normal conjunctival and nasopharyngeal flora of patients with choroidal neovascularization. — 2 years
- Monitor changes in normal conjunctival and nasopharyngeal flora after repeated exposure to topical antibiotics over a 2 year period. — 2
Countries
United States