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A Prospective, Randomized, Controlled Trial Comparing Three Different Gonadotrophin Regimens in Oocyte Donors: Ovarian Response and IVF Outcome
Exploratory study assessing the effect of three gonadotrophin protocols on Controlled Ovarian Stimulation (COS) parameters and IVF outcome in oocyte donors undergoing GnRH analogue (long protocol). 1,028 donors were randomized in three groups: Group I (n= 346) only r-FSH, Group II (n= 333) only HP-hMG and Group III (n= 349) r-FSH plus HP-hMG. IVF outcome of 1,059 oocyte recipients was compared.
Details
| Lead sponsor | Instituto Valenciano de Infertilidad, IVI VALENCIA |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Start date | 2005-01 |
| Completion | 2006-12 |
Conditions
- Ovarian Stimulation
Interventions
- r-FSH
- HP-hMG
- r-FSH plus HP-hMG
Primary outcomes
- The aim of this study was to verify whether different gonadotrophin regimes could affect controlled ovarian stimulation (COS) parameters and IVF outcome in an egg donation program. — one year
Countries
Spain