An Open-Label, Randomized Assessment of the Concentrations of Besifloxacin, Moxifloxacin, or Gatifloxacin in the Aqueous Humor of Subjects After a Single Topical Dose

NCT00824070 Phase 1 COMPLETED Results posted

This study is being conducted to assess the concentration of besifloxacin, moxifloxacin, or gatifloxacin in aqueous humor samples collected following topical instillation of the associated formulation in subjects undergoing cataract surgery.

Details

Lead sponsor	Bausch & Lomb Incorporated
Phase	Phase 1
Status	COMPLETED
Enrolment	105
Start date	2009-02
Completion	2009-08

Conditions

• Cataract Extraction

Interventions

• Besifloxacin hydrochloride
• moxifloxacin hydrochloride
• gatifloxacin

Primary outcomes

• The Aqueous Humor Drug Concentration. — Visit 2, 1-14 days following screening visit
  An aqueous humor specimen was collected from the study eye for determination of drug concentration 60 min after study drug instillation.

Countries

United States