NCT00814762 is a Phase 1 clinical trial of HIV Vaccine 732462 in AIDS, sponsored by GlaxoSmithKline.

Who is sponsoring NCT00814762?

NCT00814762 is sponsored by GlaxoSmithKline.

What drugs are being tested in NCT00814762?

Interventions in NCT00814762: HIV Vaccine 732462, Placebo vaccine.

Is NCT00814762 still recruiting?

NCT00814762 is currently completed. Last updated 18 June 2018.

Last reviewed 2018-06-18 · How we verify

NCT00814762

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Safety of the HIV Vaccine 732462 in HIV Infected Subjects Aged 18 to 55 Years Old

Completed Phase 1 Last updated 18 June 2018

What this trial tests

Phase 1 trial testing HIV Vaccine 732462 in AIDS in 41 participants. Completed in 18 August 2010.

Timeline

3 February 2009

Primary endpoint
18 August 2010

18 August 2010

Quick facts

Lead sponsor	GlaxoSmithKline
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	other
Enrollment	41
Start date	3 February 2009
Primary completion	18 August 2010
Estimated completion	18 August 2010
Sites	6 locations across Germany

Drugs / interventions tested

HIV Vaccine 732462 — full drug profile →
Placebo vaccine — full drug profile →

Conditions studied

AIDS — all drugs for AIDS →

Sponsor

GlaxoSmithKline — full company profile →

Who can join

Adults 18 to 55, any sex, with AIDS. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this research study is to evaluate the safety of GSK Biologicals' investigational HIV vaccine 732462, administered as two doses approximately 1 month apart, in a small group of HIV infected people.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

An adjuvanted polyprotein HIV-1 vaccine induces polyfunctional cross-reactive CD4+ T cell responses in seronegative volunteers.
Van Braeckel E, Bourguignon P, Koutsoukos M, Clement F, et al · · 2011 · cited 52× · PMID 21208909 · DOI 10.1093/cid/ciq160
Long-term follow-up of HIV-1-infected adults who received the F4/AS01<sub>B</sub> HIV-1 vaccine candidate in two randomised controlled trials.
Harrer T, Dinges W, Roman F, TH-HIV-011 study group. · · 2018 · cited 2× · PMID 29606517 · DOI 10.1016/j.vaccine.2018.03.043

Verify or expand the search:

Other recruiting trials for AIDS

Currently open trials in the same condition.

NCT05373758 — A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa · NA · recruiting
NCT05939167 — Mesenchymal Stem Cells Treatment for AIDS Patients at Late Stage · Phase 1, PHASE2 · recruiting
NCT06137196 — Risk Identification Factors for Pulmonary Function Impairment in AIDS Patients Recovered From Severe Pneumonia · recruiting
NCT06145841 — Metagenomic Next-Generation Sequencing Guides Anti-Infection Strategies · recruiting
NCT05988879 — Functional Cure of Hepatitis B in HIV/HBV Co-infected Patients · recruiting

Other GlaxoSmithKline trials

Trials by the same sponsor.

NCT07569081 — A Study Evaluating the Efficacy and Safety of Momelotinib in Participants With Vacuoles, E1-enzyme, X-linked, Autoinflam · Phase 2, PHASE3 · not yet recruiting
NCT07406347 — A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Infants Receiving 3-dose · Phase 1 · not yet recruiting
NCT07286266 — A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Platinum-resistant Ovarian Cancer (BEH · Phase 3 · not yet recruiting
NCT07286331 — A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Recurrent Endometrial Cancer (BEHOLD-E · Phase 3 · not yet recruiting
NCT07406334 — A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months · Phase 1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00814762 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by GlaxoSmithKline
Last refreshed: 18 June 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00814762.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing