Last reviewed · How we verify
Physiologic Monitoring of Antidepressant Treatment Response
Primary: to identify physiologic indicators of venlafaxine treatment response using quantitative EEG (QEEG) cordance, and to determine if cordance changes are specifically associated with response to venlafaxine; Secondary: to determine if cordance changes early in the course (i.e., prior to improvement in clinical symptoms) of venlafaxine (or another antidepressant if venlafaxine is not clinically indicated for a particular patient) are predictive of later clinical response.
Details
| Lead sponsor | University of California, Los Angeles |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 38 |
| Start date | 1996-11 |
| Completion | 1998-12 |
Conditions
- Major Depression
Interventions
- venlafaxine (Effexor)
- placebo
Primary outcomes
- quantitative electroencephalography (QEEG) — 6 QEEG measurements (end of wash-in, and 48 hours, 1 week, 2 weeks, 4 weeks, and 8 weeks after randomized treatment)
Countries
United States