Who is sponsoring NCT00790881?

NCT00790881 is sponsored by University of Cape Town.

What condition does NCT00790881 study?

NCT00790881 studies Malaria, HIV.

What drugs are being tested in NCT00790881?

Interventions: Artemether/Lumefantrine, Artemether/ lumefantrine.

What is the status of NCT00790881?

NCT00790881 is currently COMPLETED.

Last reviewed 2010-06-25 · How we verify

Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Nevirapine in HIV-infected Adults

NCT00790881 Phase 4 COMPLETED

Despite the clinical significance of potential interactions between antimalarials and antiretrovirals, no drug interaction studies have been published and there is an urgent need to address this gap in current knowledge. This study aims to assess the drug interaction between the antimalarial Artemether/Lumefantrine used for management of uncomplicated malaria and Nevirapine-based antiretroviral therapy.

Details

Lead sponsor	University of Cape Town
Phase	Phase 4
Status	COMPLETED
Enrolment	36
Start date	2008-10
Completion	2009-12

Conditions

Malaria
HIV

Interventions

Artemether/Lumefantrine
Artemether/ lumefantrine

Primary outcomes

Lumefantrine plasma concentration — day 7

Countries

South Africa