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Gastrointestinal Motility in Patients With Neuroendocrine Tumors-Effects of Sandostatin LAR
We will study the total gastrointestinal transit time (GITT), gastric emptying and small intestine motility in NET patients before and after treated with somatostatin analogues and compare these to healthy subjects. For this we will use radio-opaque markers and the newly developed Motility Tracking System (MTS). Hypothesis: Patients with NET and carcinoid syndrome have decreased GITT, gastric emptying and small bowel transit time and an increase in phase III MMC activity compared to healthy subjects. Treatment with somatostatin analogues increase transit times and decrease phase III MMC activity and improves the clinical symptoms.
Details
| Lead sponsor | University of Aarhus |
|---|---|
| Status | COMPLETED |
| Enrolment | 13 |
| Start date | 2008-09 |
| Completion | 2010-05 |
Conditions
- Neuroendocrine Tumor
Interventions
- Magnetic Tracking System (MTS) and radio-opaque markers
Primary outcomes
- Gastrointestinal transit time in NET patients — End of the study
Countries
Denmark