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Anti-diabetic Effect of Gynostemma Pentaphyllum Tea in Type 2 Diabetic Patients
The aim of the present study was to investigate the long-term effects on blood glucose concentrations and possible adverse effects of an extract of Gynostemma pentaphyllum (GP). This is a plant growing in the mountain regions of Northern Vietnam and previously being used in traditional medicine. The GP extract, or placebo, was randomized to newly diagnosed patients with type 2 diabetes and administered as a "tea", 3 g two times daily during 12 weeks. All patients received instructions regarding diet and physical exercise. Oral glucose tolerance tests were performed at baseline and then every 4 weeks, and blood tests were taken with the purpose to monitor lipids, kidney and liver function, body weight and blood pressure.
Details
| Lead sponsor | Hanoi Medical University |
|---|---|
| Phase | Phase 1/Phase 2 |
| Status | COMPLETED |
| Enrolment | 24 |
| Start date | 2007-02 |
| Completion | 2007-12 |
Conditions
- Type 2 Diabetes
Interventions
- Gynostemma pentaphyllum tea
- Placebo tea
Primary outcomes
- Fasting plasma glucose — 12 weeks
- HbA1c (glycosylated hemoglobin) — 12 weeks
Countries
Vietnam