The Effects of Antiepileptic Drugs on Serum Lipids and Inflammation in Patients With Subarachnoid Hemorrhage

NCT00774306 NA TERMINATED Results posted

The purpose of this study is to determine if certain seizure medications raise levels of cholesterol and other blood components which could increase the risk of heart attacks and strokes.

Details

Lead sponsor	Thomas Jefferson University
Phase	NA
Status	TERMINATED
Enrolment	52
Start date	2009-04
Completion	2012-06

Conditions

• Subarachnoid Hemorrhage

Interventions

• phenytoin
• valproate
• levetiracetam

Primary outcomes

• Change in Serum Cholesterol, Non-HDL Cholesterol, HDL Cholesterol, Lipoprotein(a), and C-reactive Protein From Baseline to Second Draw and Third Draw in Each of the 4 Study Arms — 8 weeks, 16 weeks