Effect of Pioglitazone Compared to a Combination Therapy With Ramipril and to a Ramipril Monotherapy on Low Grade Inflammation and Vascular Function in Patients With Increased Cardiovascular Risk and an Activated Inflammation. A Randomized Double-blinded Phase II Study.

NCT00770497 Phase 2 COMPLETED

The purpose of this study is to determine the effects of pioglitazone, once daily (QD), on low grade inflammation and vascular function in hypertensive patients.

Details

Lead sponsor	Takeda
Phase	Phase 2
Status	COMPLETED
Enrolment	172
Start date	2007-03
Completion	2008-05

Conditions

• Inflammation
• Hypertension

Interventions

• Pioglitazone
• Pioglitazone and ramipril
• Ramipril

Primary outcomes

• Change in the high-sensitivity C-reactive Protein value. — Week: 12.

Countries

Germany