NCT00766961

Randomized Comparison of Trans-catheter Arterial Embolization (TAE) and Surgery in Patients With Major Peptic Ulcer Bleeding Uncontrolled by Endoscopic Therapy

Terminated NA Last updated 21 June 2020

What this trial tests

NA trial testing Trans-catheter arterial embolization in Peptic Ulcer in 34 participants. Terminated before completion.

Timeline

1 April 2007

Primary endpoint
1 March 2017

1 December 2017

Quick facts

Lead sponsor	Chinese University of Hong Kong
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	34
Start date	1 April 2007
Primary completion	1 March 2017
Estimated completion	1 December 2017
Sites	1 location across China

Drugs / interventions tested

• Trans-catheter arterial embolization
• Surgery

Conditions studied

• Peptic Ulcer — all drugs for Peptic Ulcer →
• Bleeding — all drugs for Bleeding →

Sponsor

Chinese University of Hong Kong

Who can join

18 and older, any sex, with Peptic Ulcer or Bleeding. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

• Mortality within 30 days of randomization
  Time frame: 30 days
  Mortality within 30 days of randomization

Sponsor's own description

The aim of the study is to compare the outcomes of trans-catheter arterial embolization (TAE) and surgery as salvage therapy of peptic ulcer bleeding after failed endoscopic therapy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. A systematic review of transarterial embolization versus emergency surgery in treatment of major nonvariceal upper gastrointestinal bleeding.
   Beggs AD, Dilworth MP, Powell SL, Atherton H, et al · · 2014 · cited 57× · PMID 24790465 · DOI 10.2147/ceg.s56725