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Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis
The purpose of this study is to provide the necessary data and experience to design a larger, full scale clinical trial to determine if a certain medicine (repaglinide), which increases the amount of insulin secreted by the pancreas, can improve the nutritional status and pulmonary function of adolescents and young adults with cystic fibrosis and prediabetes by improving blood glucose control. The investigators are also trying to determine the relationship between systemic inflammatory factors and glucose impairment.
Details
| Lead sponsor | Arbelaez, Ana Maria |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 31 |
| Start date | 2006-11 |
| Completion | 2013-01 |
Conditions
- Cystic Fibrosis Related Diabetes
- Pancreatic Insufficiency
Interventions
- placebo
- repaglinide
Primary outcomes
- BMI — 2 year/end of study
- Body Composition — 2 year/end of study
Reporting % of Fat and Lean body mass - CRP — 2 year/end of study
Countries
United States