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NCT00755430

Structural and Functional Connectivity in Autism Spectrum Disorders

Completed Last updated 5 September 2021
What this trial tests

trial in Autism Spectrum Disorder in 130 participants. Completed in 31 December 2012.

Timeline
1 January 2009
Primary endpoint
31 December 2012
31 December 2012

Quick facts

Lead sponsorNational Taiwan University Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment130
Start date1 January 2009
Primary completion31 December 2012
Estimated completion31 December 2012
Sites1 location across Taiwan

Conditions studied

Sponsor

National Taiwan University Hospital

Who can join

Adults 3 to 15, any sex, with Autism Spectrum Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Autism spectrum disorder (ASD) has been given a high priority for genetic and neurobiological study. There is no such information in Asian population and no study has conducted using Diffusion Spectrum Imaging (DSI) to investigate the connectivity throughout the world. Moreover, no follow-up study has been done to examine the developmental changes of structural and functional connectivity. We anticipate to establishing a cohort of 50 ASD and their siblings with complete clinical, neuropsychological, brain imaging, and genetic data for longitudinal study on ASD. Our findings will contribute to our understanding of the structural and functional dysconnectivity for ASD and whether dysconnectivity can be an endophenotype for ASD and used as a biomarker for early diagnosis of ASD.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Regional brain volume differences between males with and without autism spectrum disorder are highly age-dependent.
    Lin HY, Ni HC, Lai MC, Tseng WI, et al · · 2015 · cited 62× · PMID 26045942 · DOI 10.1186/s13229-015-0022-3

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Other recruiting trials for Autism Spectrum Disorder

Currently open trials in the same condition.

Other National Taiwan University Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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