Effects of Arformoterol on Exercise Endurance Time and Breathlessness in COPD: Cycle Ergometer vs. Treadmill (ARFEET)

NCT00754546 Phase 4 COMPLETED Results posted

Previous studies suggest that treadmill exercise may be a more relevant exercise stimulus than the cycle ergometer to demonstrate benefits with bronchodilator therapy in patients with COPD. The hypothesis of the study is that patients with COPD will exhibit greater improvements in exercise endurance and breathlessness with arformoterol compared with normal saline during treadmill walking than with cycle exercise.

Details

Lead sponsor	Dartmouth-Hitchcock Medical Center
Phase	Phase 4
Status	COMPLETED
Enrolment	20
Start date	2008-08
Completion	2009-05

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

• Arformoterol tartrate
• Placebo: Normal Saline
• Treadmill Exercise
• Cycle Exercise

Primary outcomes

• Exercise Endurance Time — After one dose
  Participants were asked to exercise until symptom limitation

Countries

United States