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A Randomized Controlled Trial of Antibiotic Prophylaxis in Children With Pyelonephritis in the Abscence of Vesicoureteral Reflux
Children who present with pyelonephritis undergo many investigations, and long term care to prevent renal damage. The focus is primarily on preventing renal failure however along the way and particularly with children, other issues arise which impact their lives, as well as their family's lives. Parents are concerned about subjecting their children to invasive procedures and long term antibiotic use, particularly if they are not sure of the benefit. This study seeks to provide information on the impact of investigation and long term antibiotic treatment in reference to long term health and quality of life in children who present with febrile urinary tract infections in the absence of anatomic abnormalities.
Details
| Lead sponsor | University of Alberta |
|---|---|
| Phase | Phase 3 |
| Status | WITHDRAWN |
| Start date | 2009-02 |
| Completion | 2014-12 |
Conditions
- Pyelonephritis
Interventions
- Trimethoprim Sulfamethoxazole
- placebo
Primary outcomes
- To determine whether antibiotic prophylaxis prevents recurrent urinary tract infections by assessing if there is a decreased incidence of urinary tract infections. — one year
Countries
Canada