Who is sponsoring NCT00751855?

NCT00751855 is sponsored by VISN 3 Mental Illness Research, Education and Clinical Center.

What drugs are being tested in NCT00751855?

Interventions: Prolonged Exposure therapy, Hydrocortisone, placebo.

What is the status of NCT00751855?

NCT00751855 is currently COMPLETED.

Last reviewed 2012-07-26 · How we verify

Cortisol Augmentation of Prolonged Exposure Therapy

NCT00751855 NA COMPLETED

This study seeks to examine the efficacy of hydrocortisone administration in the augmentation of the therapeutic effects of Prolonged Exposure (PE) therapy, an empirically tested treatment shown to be effective in the the treatment of posttraumatic stress disorder (PTSD). The augmentation builds on both the translation of neuroscience findings demonstrating the effects of glucocorticoids (GCs) on learning, and on empirical clinical findings from other investigators demonstrating beneficial effects of GCs in reducing traumatic memories in trauma-exposed persons.

Details

Lead sponsor	VISN 3 Mental Illness Research, Education and Clinical Center
Phase	NA
Status	COMPLETED
Enrolment	11
Start date	2008-07
Completion	2011-02

Conditions

PTSD

Interventions

Prolonged Exposure therapy
Hydrocortisone
placebo

Primary outcomes

Change in PTSD symptom severity as assessed by the Clinician Administered PTSD Scale (CAPS) — Baseline (Week 0), endpoint (week 11)

Countries

United States