Use of Sevelamer Hydrochloride to Control Hyperphosphatemia and Reduce Calcification Burden in the Poor Peritoneal Dialysis Patients (SERENE)

NCT00745589 NA COMPLETED

To test the hypothesis that second-line fixed low-dose sevelamer hydrochloride therapy is as effective as first-line high-dose sevelamer hydrochloride therapy in limiting the progression of cardiovascular calcification.

Details

Lead sponsor	The University of Hong Kong
Phase	NA
Status	COMPLETED
Enrolment	60
Start date	2008-07
Completion	2015-01

Conditions

• Endstage Renal Disease

Interventions

• sevelamer hydrochloride

Primary outcomes

• Changes in coronary artery, aortic valve, mitral annulus calcium scores — over 24 months
  Vascular and valvular calcium scores

Countries

Hong Kong