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Oral Glyceryl Triacetate (GTA) in Newborns With Canavan
Canavan disease is caused by Aspartoacylase deficiency. There is no treatment for the disease, but there is a food additive that includes acetate . We suggest an early treatment with acetate and a neurologic evaluation, including MRI, after 4 months of treatment. In any case the treatment will be stopped at the age of 22 months, when myelinization is ended.
Details
| Lead sponsor | Shaare Zedek Medical Center |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 1 |
| Start date | 2008-03 |
Conditions
- Canavan Disease
Interventions
- GTA (Glyceryl triacetate)
- GTA glyceryl triacetate
Primary outcomes
- brain MRI at the end of the study — 6 months
Countries
Israel