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NCT00708045: Chemobrain
A Multi-modality Imaging Assessment of Chemobrain
Phase 1 trial testing [18F]fluoro-2-deoxy-D-glucose (FDG) in Cancer in 34 participants. Completed in 5 February 2015.
5 February 2015
Quick facts
| Lead sponsor | University of Utah |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 34 |
| Start date | 9 May 2007 |
| Primary completion | 5 February 2015 |
| Estimated completion | 5 February 2015 |
| Sites | 1 location across United States |
Drugs / interventions tested
- [18F]fluoro-2-deoxy-D-glucose (FDG) — full drug profile →
Conditions studied
- Cancer — all drugs for Cancer →
Sponsor
University of Utah
Who can join
Adults 18 to 65, female only, with Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients must have had their breast cancer treated at the Huntsman Cancer Institute to be eligible for this trial. OBJECTIVES: To use quantitative FDG-positron emission tomography (PET), functional MRI (fMRI) and co-registered anatomic MRI imaging to better understand the cognitive disorder known as "chemobrain" which effects up to 16 -50% of individuals receiving long-term adjuvant chemotherapy \[Tannock 2004, Matsuda 2005\]. The study is exploratory to obtain proof of feasibility pilot data to support an eventual submission to the NIH. Neuropsychological Testing A battery of testing will be used to assess the subjective complaints of cognitive impairment in the symptomatic patient cohort. Similarly the same battery of tests will be used to assure that the non-symptomatic patient control group and the age-matched normal controls do not exhibit any cognitive impairment. The following set of clinical tests will be performed to assess the degree of cognitive impairment in all subjects.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00708045
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT00813566 — Multi-Tracer PET Assessment of Primary Brain Tumors · Phase 1 · completed
- NCT00707213 — FDG-Positron Emission Tomography (PET)/CT In the Evaluation of Persistent Febrile Neutropenia in Cancer Patients · Phase 1 · terminated
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Currently open trials in the same condition.
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Other University of Utah trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00708045 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Utah
- Last refreshed: 15 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00708045.
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