A Study to Evaluate the Effectiveness of Induced Diuresis With Matched Hydration Therapy Compared to Standard Overnight Hydration in the Prevention of Contrast Induced Nephropathy -MYTHOS Study

NCT00702728 Phase 3 UNKNOWN

This study is being proposed with the objective to assess the potential benefits of induced diuresis by furosemide with matched hydration therapy compared to standard hydration in the prevention of contrast-induced nephropathy (CIN). It is expected that matched hydration will prove to be as effective as hydration alone, will avoid an overnight stay prior to the procedure, and thus will prove to be a less costly and more clinically manageable solution to the prevention of CIN.

Details

Lead sponsor	Centro Cardiologico Monzino
Phase	Phase 3
Status	UNKNOWN
Enrolment	120
Start date	2008-06
Completion	2009-12

Conditions

• Contrast Induced Nephropathy

Interventions

• Furosemide and matched saline hydration
• isotonic saline solution

Primary outcomes

• Incidence of CIN — 48-72 hours

Countries

Italy