NCT00700596 is a EARLY_PHASE1 clinical trial of Salvinorin A in Healthy, sponsored by Yale University.

Who is sponsoring NCT00700596?

NCT00700596 is sponsored by Yale University.

What drugs are being tested in NCT00700596?

Interventions in NCT00700596: Salvinorin A, Placebo.

Is NCT00700596 still recruiting?

NCT00700596 is currently completed. Last updated 7 April 2022.

Last reviewed 2022-04-07 · How we verify

NCT00700596

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Salvinorin A in Healthy Controls

Completed EARLY_PHASE1 Last updated 7 April 2022

What this trial tests

EARLY_PHASE1 trial testing Salvinorin A in Healthy in 105 participants. Completed in 22 August 2014.

Timeline

12 February 2009

Primary endpoint
22 August 2014

22 August 2014

Quick facts

Lead sponsor	Yale University
Phase	EARLY_PHASE1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	basic science
Enrollment	105
Start date	12 February 2009
Primary completion	22 August 2014
Estimated completion	22 August 2014
Sites	1 location across United States

Drugs / interventions tested

Salvinorin A — full drug profile →
Placebo

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Yale University

Who can join

Adults 18 to 45, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study evaluates the effects of Salvinorin A (SA). SA is the active ingredient of the plant Salvia divinorum that is known to have been used by Mexican Indians as part of religious rituals. The purpose of this project is to understand what people experience when they consume Salvinorin A.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The Kappa Opioid Receptor: A Promising Therapeutic Target for Multiple Pathologies.
Dalefield ML, Scouller B, Bibi R, Kivell BM. · · 2022 · cited 70× · PMID 35795569 · DOI 10.3389/fphar.2022.837671
The Use of Psychedelics in the Treatment of Medical Conditions: An Analysis of Currently Registered Psychedelics Studies in the American Drug Trial Registry.
Kurtz JS, Patel NA, Gendreau JL, Yang C, et al · · 2022 · cited 19× · PMID 36259015 · DOI 10.7759/cureus.29167

Verify or expand the search:

Other trials of Salvinorin A

Trials testing the same drug.

NCT03418714 — Effects of Salvinorin A on Brain Function · Phase 1, PHASE2 · completed

Other recruiting trials for Healthy

Currently open trials in the same condition.

NCT06707207 — Predicting Future Errors During Skill Performance · recruiting
NCT07169630 — PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) · Phase 1 · recruiting
NCT07499414 — The Effects of the Bile Acid Supplement, 7-keto Lithocholic Acid, on Human Gut Microbiota and Risk Factors for Disease. · NA · recruiting
NCT07496697 — Effects of Electroacupuncture at NP82 and SP15 on Bowel Motility in Healthy Subjects · NA · recruiting
NCT06431932 — Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity · Phase 1, PHASE2 · recruiting

Other Yale University trials

Trials by the same sponsor.

NCT06900998 — Pilot Study: Effects of Nimodipine on Alcohol Drinking · Phase 2 · not yet recruiting
NCT04910984 — Developing a Chatbot to Promote HIV Testing · NA · not yet recruiting
NCT07458087 — Accuracy of the Accuro 3S · NA · not yet recruiting
NCT07398404 — A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Pa · Phase 1, PHASE2 · not yet recruiting
NCT07305324 — Improving Liver Fibrosis Diagnosis in Primary Care Using FibroX AI · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00700596 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yale University
Last refreshed: 7 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00700596.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing