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NCT00696371
PET Imaging of Peripheral Benzodiazepine Receptors
trial in Healthy in 15 participants. Completed in 19 August 2014.
Quick facts
| Lead sponsor | National Institute of Mental Health (NIMH) |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 15 |
| Start date | 6 June 2008 |
| Estimated completion | 19 August 2014 |
| Sites | 1 location across United States |
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
National Institute of Mental Health (NIMH)
Who can join
18 and older, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will use positron emission tomography (PET) to measure a receptor in the brain that is involved in inflammation. It will test two radioactive chemicals used in the procedure to see if the newer chemical, \[(11)C\]B, is as good or better than the older one, \[(11)C\]A, for measuring brain inflammation. Healthy volunteers 18 years of age and older may be eligible for this study. Participants undergo an evaluation, \[(11)C\]A PET scan, \[(11)C\]B PET scan and magnetic resonance imaging (MRI), as follows: Evaluation Medical history and physical examination, blood and urine tests PET scans * \[(11)C\]A scan. A catheter (plastic tube) is placed in an arm vein for injection of the \[(11)C\]A isotope. Some patients also have a catheter placed in an artery in the wrist to collect arterial blood samples during the scan. Subjects then lie on the scanner bed and a special mask is fitted to the head to help keep the subject s head still during the procedure. Following an 8-minute scan to calibrate the scanner, the \[(11)C\]A is injected into the catheter in the vein and pictures are taken that show where chemicals related to inflammation are present. The procedure takes about 2.5 hours. * \[(11)C\]B scan. The procedure is the same as above for \[(11)C\]A, except the isotope used is \[(11)C\]B. MRI scan. This test uses a strong magnetic field and radio waves to obtain images of body organs and tissues. The subject lies on a table that can slide in and out of the scanner (a metal cylinder), wearing earplugs to muffle loud noises that occur during the scan. ...
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00696371
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other National Institute of Mental Health (NIMH) trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00696371 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Mental Health (NIMH)
- Last refreshed: 17 December 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00696371.
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