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Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of celecoxib may keep polyps and colorectal cancer from forming in patients with familial adenomatous polyposis. PURPOSE: This randomized phase I trial is studying the side effects and best dose of celecoxib in treating young patients with a genetic predisposition for familial adenomatous polyposis.
Details
| Lead sponsor | M.D. Anderson Cancer Center |
|---|---|
| Phase | PHASE1 |
| Status | COMPLETED |
| Enrolment | 22 |
| Start date | Thu Nov 21 2002 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Fri Apr 21 2006 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Colorectal Cancer
- Precancerous Condition
Interventions
- celecoxib
- placebo
Countries
United States