NCT00676234 is a Phase 2 clinical trial of epoetinum in Acute Renal Failure, sponsored by University Hospital, Geneva.

Who is sponsoring NCT00676234?

NCT00676234 is sponsored by University Hospital, Geneva.

What drugs are being tested in NCT00676234?

Interventions in NCT00676234: epoetinum.

What condition does NCT00676234 study?

NCT00676234 studies Acute Renal Failure.

Is NCT00676234 still recruiting?

NCT00676234 is currently completed. Last updated 26 June 2009.

Last reviewed 2009-06-26 · How we verify

NCT00676234

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Recombinant Human Erythropoietin Use in ICU Patients: Does it Prevent Acute Renal Failure?

Completed Phase 2 Last updated 26 June 2009

What this trial tests

Phase 2 trial testing epoetinum in Acute Renal Failure in 80 participants. Completed in 1 June 2009.

Timeline

1 May 2008

Primary endpoint
1 June 2009

1 June 2009

Quick facts

Lead sponsor	University Hospital, Geneva
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	80
Start date	1 May 2008
Primary completion	1 June 2009
Estimated completion	1 June 2009
Sites	1 location across Switzerland

Drugs / interventions tested

epoetinum — full drug profile →

Conditions studied

Acute Renal Failure — all drugs for Acute Renal Failure →

Sponsor

University Hospital, Geneva

Who can join

18 and older, any sex, with Acute Renal Failure. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

mean change (%) from baseline in urinary NGAL concentration at 96 hr after rhu EPO injection
Time frame: 4 days

Sponsor's own description

Pilot study aiming to assess the effect of two doses of rhu EPO on urine NGAL concentration and on serum cystatin C and creatinine levels in critically ill patients at risk of ARF.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Epoetin administrated after cardiac surgery: effects on renal function and inflammation in a randomized controlled study.
de Seigneux S, Ponte B, Weiss L, Pugin J, et al · · 2012 · cited 45× · PMID 23033926 · DOI 10.1186/1471-2369-13-132
Bridging translation for acute kidney injury with better preclinical modeling of human disease.
Skrypnyk NI, Siskind LJ, Faubel S, de Caestecker MP. · · 2016 · cited 41× · PMID 26962107 · DOI 10.1152/ajprenal.00552.2015
Use of high-dose erythropoietin for repair after injury: A comparison of outcomes in heart and kidney.
Gobe GC, Morais C, Vesey DA, Johnson DW. · · 2013 · cited 18× · PMID 24475445 · DOI 10.12860/jnp.2013.27
Harms of off-label erythropoiesis-stimulating agents for critically ill people.
Mesgarpour B, Heidinger BH, Roth D, Schmitz S, et al · · 2017 · cited 17× · PMID 28841235 · DOI 10.1002/14651858.cd010969.pub2
Erythropoietin in the critically ill: do we ask the right questions?
McCook O, Georgieff M, Scheuerle A, Möller P, et al · · 2012 · cited 10× · PMID 23016869 · DOI 10.1186/cc11430

Verify or expand the search:

Other recruiting trials for Acute Renal Failure

Currently open trials in the same condition.

NCT04334707 — Kidney Precision Medicine Project · recruiting

Other University Hospital, Geneva trials

Trials by the same sponsor.

NCT07506356 — Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors · recruiting
NCT07267624 — EARLY Antibiotics aDAptation in Severe Pneumonia(The EARLY ADAPT Study) · NA · not yet recruiting
NCT06710210 — Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventi · NA · not yet recruiting
NCT07173348 — Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea · NA · not yet recruiting
NCT07129655 — Cholangitis Definition and Treatment After Kasai Hepatoportoenterostomy for Biliary Atresia: TRACK-BA Study (TRacking Ch · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00676234 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Geneva
Last refreshed: 26 June 2009

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00676234.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing