NCT00675064 is a Phase 1 clinical trial of GSK369796 in Malaria, sponsored by GlaxoSmithKline.

Who is sponsoring NCT00675064?

NCT00675064 is sponsored by GlaxoSmithKline.

What drugs are being tested in NCT00675064?

Interventions in NCT00675064: GSK369796, Placebo.

Is NCT00675064 still recruiting?

NCT00675064 is currently completed. Last updated 13 September 2018.

Last reviewed 2018-09-13 · How we verify

NCT00675064

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects

Completed Phase 1 Last updated 13 September 2018

What this trial tests

Phase 1 trial testing GSK369796 in Malaria in 41 participants. Completed in 12 October 2008.

Timeline

2 May 2008

Primary endpoint
12 October 2008

12 October 2008

Quick facts

Lead sponsor	GlaxoSmithKline
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	41
Start date	2 May 2008
Primary completion	12 October 2008
Estimated completion	12 October 2008
Sites	1 location across United Kingdom

Drugs / interventions tested

GSK369796 — full drug profile →
Placebo

Conditions studied

Malaria — all drugs for Malaria →

Sponsor

GlaxoSmithKline — full company profile →

Who can join

Adults 18 to 40, any sex, with Malaria. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will examine safety of single doses of GSK369796 in healthy subjects, along with some test to examine how quickly GSK369796 gets in your blood, and how long it takes your body to get rid of it.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The past, present and future of anti-malarial medicines.
Tse EG, Korsik M, Todd MH. · · 2019 · cited 260× · PMID 30902052 · DOI 10.1186/s12936-019-2724-z
Therapeutic Approaches for Zika Virus Infection of the Nervous System.
Abrams RPM, Solis J, Nath A. · · 2017 · cited 24× · PMID 28952036 · DOI 10.1007/s13311-017-0575-2

Verify or expand the search:

Other recruiting trials for Malaria

Currently open trials in the same condition.

NCT07358910 — Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective · recruiting
NCT07036159 — A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months · Phase 2 · recruiting
NCT06735209 — First-in-Human PfSPZ-LARC2 Vaccination/CHMI · Phase 1 · active not recruiting
NCT06854042 — A Study of Oral E1018 in Healthy Adult Participants · Phase 1 · recruiting
NCT06607003 — Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Cha · Phase 1 · recruiting

Other GlaxoSmithKline trials

Trials by the same sponsor.

NCT07569081 — A Study Evaluating the Efficacy and Safety of Momelotinib in Participants With Vacuoles, E1-enzyme, X-linked, Autoinflam · Phase 2, PHASE3 · not yet recruiting
NCT07406347 — A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Infants Receiving 3-dose · Phase 1 · not yet recruiting
NCT07286266 — A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Platinum-resistant Ovarian Cancer (BEH · Phase 3 · not yet recruiting
NCT07286331 — A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Recurrent Endometrial Cancer (BEHOLD-E · Phase 3 · not yet recruiting
NCT07406334 — A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months · Phase 1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00675064 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by GlaxoSmithKline
Last refreshed: 13 September 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00675064.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing