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Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma
This phase II trial studies how well combination chemotherapy with or without rituximab works in treating participants with stage III-IV classic Hodgkin lymphoma. Monoclonal antibodies, such as rituximab, may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as doxorubicin hydrochloride, bleomycin, vinblastine, and dacarbazine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving rituximab with combination chemotherapy may work better in treating participants with classic Hodgkin lymphoma.
Details
| Lead sponsor | M.D. Anderson Cancer Center |
|---|---|
| Phase | PHASE2 |
| Status | COMPLETED |
| Enrolment | 58 |
| Start date | Wed Mar 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Wed Sep 05 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Classic Hodgkin Lymphoma
- Lugano Classification Stage III Hodgkin Lymphoma AJCC v8
- Lugano Classification Stage IV Hodgkin Lymphoma AJCC v8
Interventions
- Bleomycin
- Dacarbazine
- Doxorubicin Hydrochloride
- Rituximab
- Vinblastine
Countries
United States