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Evaluation of a Primary Treatment Algorithm Using Combination Therapy for the Management of Patients With Hypertension and Hypercholesterolemia (STITCH2)
The objective of this study is to assess if the implementation of a treatment algorithm including initial treatment with a low dose diuretic/ACE-inhibitor or ARB combination and subsequently a low dose DHP-CCB/statin combination will improve the management of hypertension/hypercholesterolemia compared to guidelines-base management at family practices.
Details
| Lead sponsor | University of Western Ontario, Canada |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 1000 |
| Start date | 2008-02 |
| Completion | 2010-12 |
Conditions
- Hypertension
- Hypercholesterolemia
Interventions
- Treatment algorithm:caduet, Amlodipine, ACEI-ARB combo dose, a-blocker, b-blocker or spironolactone, dyslipidemic therapy with ezetamide
Primary outcomes
- Proportion of subjects whose systolic BP [SBP] <140 mmHg and diastolic BP [DBP] <90 mmHg)or proportion whose cholesterol levels are at or below threshold based on their global artherosclerotic risk profile compared at the practice level. — 6 months
Countries
Canada