A Prospective Randomised Study to Evaluate the Effect of Triggering Ovulation With GnRHa (Buserelin) and Low Dose hCG (Pregnyl) as Compared to the Use of Conventional Doses of hCG (Pregnyl)

NCT00627406 Phase 4 COMPLETED Results posted

The purpose of this study is to possibly further improve the clinical outcome and explore the incidence of OHSS in patients, who have final oocyte maturation with GnRHa (Buserelin) in GnRH antagonist IVF/ICSI cycles

Details

Lead sponsor	Regionshospitalet Viborg, Skive
Phase	Phase 4
Status	COMPLETED
Enrolment	384
Start date	2009-01
Completion	2011-12

Conditions

• OHSS (Ovarian Hyperstimulation)

Interventions

• Buserelin and Pregnyl
• Pregnyl
• Buserelin and Pregnyl
• Pregnyl

Primary outcomes

• Frequency of Moderate to Severe OHSS. — From the date of triggering ovulation until 2 weeks after pregnancy test. group C and D. 12 days after pregnancy test

Countries

Denmark