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NCT00626366

Distribution of Topical Nasal Medication Within the Nasal Cavity and Sinuses by Radiographic Comparison

Completed NA Results posted Last updated 28 September 2023
What this trial tests

NA trial testing Sinus CT Scan in Chronic Sinusitis in 18 participants. Completed in 9 January 2009.

Timeline
12 March 2008
Primary endpoint
9 January 2009
9 January 2009

Quick facts

Lead sponsorUniversity of Nebraska
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designsingle group
Maskingsingle
Primary purposeother
Enrollment18
Start date12 March 2008
Primary completion9 January 2009
Estimated completion9 January 2009
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Nebraska

Who can join

19 and older, any sex, with Chronic Sinusitis. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

To Measure the Distribution of Nasal Sprays and Drops. Primary · 2 months

CT scan scored for distribution contrast delivered by nasal spray or drops within subsets in the nasal cavity. The sinonasal cavity was divided into twenty-one subsites on each side of the nasal cavity. The interpreters scored for the presence (1) or absence (0) of contrast from the nasal spray or nasal drops within each subsite. Left and right sides were interpreted separately for a possible total score of 0-42 for each CT scan.

Nasal vestibule
GroupValue95% CI
Nasal Spray18
Nasal Drops17
Inferior upper nasal vault
GroupValue95% CI
Nasal Spray16
Nasal Drops17
Superior upper nasal vault
GroupValue95% CI
Nasal Spray0
Nasal Drops6
Anterior floor of nose
GroupValue95% CI
Nasal Spray12
Nasal Drops4
Anterior inferior meatus
GroupValue95% CI
Nasal Spray16
Nasal Drops0
Anterior inferior nasal cavity
GroupValue95% CI
Nasal Spray15
Nasal Drops6
Posterior floor of nose
GroupValue95% CI
Nasal Spray9
Nasal Drops0
Posterior inferior meatus
GroupValue95% CI
Nasal Spray9
Nasal Drops1

Sponsor's own description

The purpose of this study is to determine the distribution of nasal sprays and nasal drops when used.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other University of Nebraska trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00626366.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing