Who is sponsoring NCT00611975?

NCT00611975 is sponsored by Weill Medical College of Cornell University.

What drugs are being tested in NCT00611975?

Interventions: Fluoxetine, Bupropion.

What is the status of NCT00611975?

NCT00611975 is currently COMPLETED.

Last reviewed 2020-11-16 · How we verify

Effect of Serotonin Reuptake Inhibitors on Gonadal Steroid Hormones

NCT00611975 Phase 4 COMPLETED Results posted

This study will evaluate the effect of antidepressants on sex hormone levels in women and if the potential changes in sex hormone levels are related to sexual side effects.

Details

Lead sponsor	Weill Medical College of Cornell University
Phase	Phase 4
Status	COMPLETED
Enrolment	83
Start date	2005-10
Completion	2008-09

Conditions

Healthy

Interventions

Fluoxetine
Bupropion

Primary outcomes

Change in 17-OH Pregnenolone — Measured in baseline menstrual cycle and during antidepressant treatment for two menstrual cycles
Hormone levels at early follicular, ovulation, and luteal phase of 3 menstrual cycles which included baseline, month 1 of daily antidepressant treatment and month 2 of daily antidepressant treatment. Effects of the two antidepressant treatments and menstrual cycle on hormone level were examined.