The Japan-Combined Treatment With Olmesartan and a Calcium Channel Blocker Versus Olmesartan and Diuretics Randomized Efficacy Study (J-CORE)

NCT00607035 Phase 4 COMPLETED

The purpose of this study is to investigate which combination therapy is more effective for improving the blood pressure (BP) and reducing target organ damage in Japanese hypertensive patients: Angiotensin II receptor blocker (ARB) plus calcium channel blocker (CCB) or ARB plus diuretics.

Details

Lead sponsor	Jichi Medical University
Phase	Phase 4
Status	COMPLETED
Enrolment	220
Start date	2006-05
Completion	2008-05

Conditions

• Hypertension

Interventions

• Olmesartan medoxomil ＋Azelnidipine
• Olmesartan medoxomil + Hydrochlorothiazide

Primary outcomes

• Changes in central BP and ambulatory BP — 6 months

Countries

Japan