NCT00604617 is a clinical trial of Interferon-Gamma Release Assay in Tuberculosis, sponsored by Case Western Reserve University.

Who is sponsoring NCT00604617?

NCT00604617 is sponsored by Case Western Reserve University.

What drugs are being tested in NCT00604617?

Interventions in NCT00604617: Interferon-Gamma Release Assay, RT-23.

What condition does NCT00604617 study?

NCT00604617 studies Tuberculosis, HIV.

Is NCT00604617 still recruiting?

NCT00604617 is currently completed. Last updated 18 January 2022.

Last reviewed 2022-01-18 · How we verify

NCT00604617

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Interferon-Gamma Release Assays in Tuberculosis (TB) - HIV Co-infected Children

Completed Last updated 18 January 2022

What this trial tests

trial testing Interferon-Gamma Release Assay in Tuberculosis in 564 participants. Completed in 21 August 2012.

Timeline

26 January 2009

Primary endpoint
21 August 2012

21 August 2012

Quick facts

Lead sponsor	Case Western Reserve University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	564
Start date	26 January 2009
Primary completion	21 August 2012
Estimated completion	21 August 2012
Sites	1 location across South Africa

Drugs / interventions tested

Interferon-Gamma Release Assay
RT-23 — full drug profile →

Conditions studied

Tuberculosis — all drugs for Tuberculosis →
HIV — all drugs for HIV →

Sponsor

Case Western Reserve University

Who can join

Adults 3 Months to 5, any sex, with Tuberculosis or HIV. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Tuberculosis (TB) is a disease affecting the lungs that is caused by a germ spread by coughing. TB infection is currently diagnosed by a skin test that has limited accuracy. The purpose of this study is to look at the reliability of a new blood test for diagnosing TB infection in children. Study participants will include 300 HIV-infected (HIV infection is a viral infection that causes disease which destroys the body's ability to protect itself from infection and disease.) children and 500 HIV-uninfected children, ages 3 months to 5 years, residing in the Khayelitsha and Ravensmead/Uitsig Communities of the Western Cape Province, South Africa. Study procedures will include questionnaires, HIV and TB testing, which will be performed by blood and skin tests. Participants may be involved in study related procedures for up to 24 months.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Other Case Western Reserve University trials

Trials by the same sponsor.

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NCT07214233 — Youth Empowerment and Safety Intervention · NA · recruiting
NCT07225582 — Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia · NA · recruiting
NCT07217249 — Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00604617 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Case Western Reserve University
Last refreshed: 18 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00604617.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing