NCT00583180 is a clinical trial of Capsaicin in Primary Hyperalgesia, sponsored by Rigshospitalet, Denmark.

Who is sponsoring NCT00583180?

NCT00583180 is sponsored by Rigshospitalet, Denmark.

What drugs are being tested in NCT00583180?

Interventions in NCT00583180: Capsaicin.

What condition does NCT00583180 study?

NCT00583180 studies Primary Hyperalgesia.

Is NCT00583180 still recruiting?

NCT00583180 is currently completed. Last updated 29 January 2008.

Last reviewed 2008-01-29 · How we verify

NCT00583180

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cutaneous Sensory Function After Wound Instillation of Capsaicin During Groin Hernia Repair

Completed Last updated 29 January 2008

What this trial tests

trial testing Capsaicin in Primary Hyperalgesia in 42 participants. Completed in 1 January 2008.

Timeline

1 January 2008

Quick facts

Lead sponsor	Rigshospitalet, Denmark
Status	Completed
Study type	OBSERVATIONAL
Enrollment	42
Start date	1 January 2008
Estimated completion	1 January 2008
Sites	1 location across Denmark

Drugs / interventions tested

Capsaicin (CAPSAICIN) — full drug profile →

Conditions studied

Primary Hyperalgesia — all drugs for Primary Hyperalgesia →

Sponsor

Rigshospitalet, Denmark

Who can join

18 and older, male only, with Primary Hyperalgesia. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

changes in sensory function before and 2 years after groin hernia repair in patients with and without capsaicin instillation, evaluated by quantitative sensory testing
Time frame: 2 years

Sponsor's own description

The use of capsaicin as a potential analgesic drug for postoperative pain relies on the ability of capsaicin to induce membrane lysis of c-nerve fibers. In a previous randomized placebo controled blinded study of this effect we found a significant effect of capsaicin versus placebo. Before surgery all patients were examined by quantitative sensory testing to evaluate sensory function. In this study an identical sensory testing will examine if changes to the sensory function in capsaicin treated patients is identical to placebo treated patients.No new intervention will be performed

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Capsaicinoids in the treatment of neuropathic pain: a review.
Peppin JF, Pappagallo M. · · 2014 · cited 68× · PMID 24409200 · DOI 10.1177/1756285613501576

Verify or expand the search:

Other trials of Capsaicin

Trials testing the same drug.

NCT07237022 — The Role of TRP Channels in DPN · recruiting
NCT06809569 — A Study to Evaluate Laser Speckle Contrast Imaging to Assess Changes in Chemical Agent-Induced Skin Blood Flow in Health · Phase 1 · completed
NCT05958173 — Effects of 6-month of Treatment With TRPV1 and TRPA1 Agonists in Older Patients With OD · NA · unknown
NCT05983263 — Analgesic Efficacy of Capsaicin 8% Patch (QUTENZA®) in Coccygodygnia · unknown
NCT05543837 — Capsaicin for Cerebral Perfusion Augmentation · Phase 2 · completed

Other Rigshospitalet, Denmark trials

Trials by the same sponsor.

NCT07401368 — Clinicians' Trust in AI-Based Fetal Growth Estimates · NA · not yet recruiting
NCT07442357 — The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial · NA · not yet recruiting
NCT07528729 — Alcohol as a Modifiable Risk Factor for Atrial Fibrillation · NA · not yet recruiting
NCT07511439 — Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission · Phase 4 · not yet recruiting
NCT07467187 — Invasive Home Ventilation in Denmark · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00583180 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Rigshospitalet, Denmark
Last refreshed: 29 January 2008

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00583180.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing