Quetiapine Augmentation Versus Clomipramine Augmentation of Selective Serotonin Reuptake Inhibitors for Obsessive-compulsive Disorder Patients That do Not Respond to a SSRI Trial: a Randomized Open-trial. (QCAT)

NCT00564564 Phase 4 COMPLETED

The objective of this trial is to compare in an open trial format the efficacy of association of clomipramine and quetiapine with SSRI after SSRI treatment failed to produce complete remission of obsessive compulsive disorder symptoms.

Details

Lead sponsor	University of Sao Paulo
Phase	Phase 4
Status	COMPLETED
Enrolment	21
Start date	2006-01
Completion	2007-12

Conditions

• Obsessive Compulsive Disorder

Interventions

• Quetiapine
• Clomipramine

Primary outcomes

• YBOCS — 12 weeks
  difference between initial and final (12 week) Yale Brown Obsessive Compulsive Scale (YBOCS)score

Countries

Brazil